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Cost of trazodone 50 mg. This article is licensed under the Creative Commons Attribution 4.0 International License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated. We observed that trazodone-related liver injury and death was dose-dependent. Patients with a dose higher than the maximum allowed daily dose (approximately 600 mg/day), also experienced increasing frequency of hepatotoxicity and died as well. Patients with the lowest dose of trazodone (approximately 3 g/day) showed no Trazodone 100mg $149.39 - $0.83 Per pill evidence of toxicity. The doses trazodone above 600 mg/day were associated with severe liver damage (Figure ). After three months of treatment with trazodone 50 mg or lower, a total of 14 patients with TRD-related liver disease were included. All 14 patients (13 males and 2 females) were in good health and had no underlying liver diseases or major comorbidities. They were treated with either standard or extended-release trazodone in double-blind, randomized, crossover design. Before and after treatment, patients were asked to have a clinical examination every 6 months to rule out any new liver disorders. enzyme levels were checked monthly. Hepatochemistry (liver function testing with TUNEL and MTT) was performed in all patients at baseline and the end of therapy with trazodone 50 mg or lower. All patients received vitamin B12 by gavage 3 weeks before and 15 after treatment. DISCUSSION In this study, we evaluated the incidence of prices of trazodone hepatotoxicity with trazodone 50 mg, the dose that was previously considered to induce toxicity in TRD patients generic trazodone cost (3, 9). After 6 months of treatment, we observed 14 patients having at least one event trazodone for sleep and weight loss which is suggestive of hepatotoxicity; in seven these patients, the number of patients with additional events beyond that of acute toxicity was more than that for the average number of events observed in other placebo-controlled trials which used the same drug (30%-43% in six such trials). The mechanism Price of generic prozac without insurance of toxicity seen with trazodone at doses higher than the currently recommended therapy (400 mg per day) includes oxidative stress, decreased renal excretion of bile acids, and increased plasma levels of the hepatolytic factor and cytochrome P decreased P-450 enzyme activities and hepatic compared with what was observed in the placebo-controlled trials which used same drug (3, 8, 9, 12, 13).

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